Search for posts by JoannaBowie1
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Diatomite Imaging Services
from JoannaBowie1 on 01/31/2023 10:04 AMDiatomite is a very attractive natural material characterized by high porosity, high permeability, and large surface area. At the iEM Platform, Creative Biostructure supports the use of state-of-the-art instrumentation for the characterization of morphology, chemical composition, and crystalline structure of both natural and man-made solid materials. Diatomite Imaging Services https://iem.creative-biostructure.com/diatomite-characterization-using-the-iem-platform.html
ReplyGold Nanoparticle Imaging Services
from JoannaBowie1 on 01/31/2023 10:04 AMGold nanoparticles (AuNPs) are one of the most commonly utilized nanomaterials due to their unique properties, such as their stability and optical properties. In order to promote AuNPs applications in medicine and pharmacology, accurate sample characterization is needed but technically demanding. Here, we offer high-quality imaging techniques to analyze AuNPs, including transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Gold Nanoparticle Imaging Services https://iem.creative-biostructure.com/gold-nanoparticle-characterization-using-the-iem-platform.html
de novo drug design solutions
from JoannaBowie1 on 01/31/2023 10:04 AMCreative Biostructure offers de novo design solutions to help you identify new leads or to produce novel molecular scaffolds and bioisosteric equivalent for already determined or undesired fragments. de novo drug design solutions https://drug-discovery.creative-biostructure.com/de-novo-drug-design-p24
isothermal titration calorimetry fragment screening
from JoannaBowie1 on 01/31/2023 09:50 AMCreative Biostructure offers advanced isothermal titration calorimetry (ITC) services for researchers with drug discovery needs in academic institutions, biotech, and pharmaceutical industries around the world. The ITC is a powerful tool for measuring the thermodynamic parameters and binding kinetics of inter-molecular interactions without labeling, playing an important role in lead discovery and optimization processes. isothermal titration calorimetry fragment screening https://drug-discovery.creative-biostructure.com/maghelix-isothermal-titration-calorimetry-itc-p51
COVID-19 Virtual Screening
from JoannaBowie1 on 01/31/2023 09:50 AMThere are currently no approved antiviral drugs for treating coronavirus infections. In the face of an acute outbreak, we hope to adopt a more efficient approach to develop antiviral drugs. There are two main methods for drug screening, including high-throughput screening (HTS) and virtual screening. The HTS method realizes automatic operation and sensitive detection, but the positive rate is low (less than 1/10000), thus the cost is relatively high. However, the positive rate of high-throughput virtual screening is generally around 5%-20%. And the results of virtual screening can be combined with experimental screening to complement each other. Thus, virtual screening has become a classic and efficient method for lead compound discovery. Creative Biostructure can perform large-scale high-throughput virtual screening against multiple public/commercial chemical databases and our established databases of commonly used antiviral drugs, winning valuable time for your project on the development of antiviral drugs specific for coronaviruses. COVID-19 Virtual Screening https://www.creative-biostructure.com/coronavirus/virtual-screening-for-the-antiviral-drug-discovery-of-coronavirus-p21.htm
Coronavirus Surface Plasmon Resonance
from JoannaBowie1 on 01/31/2023 09:50 AMCreative Biostructure is a leading service supplier in the field of structural biology with a team of specialists specializing in contract research services for basic and preclinical research related to coronavirus infection. Currently, we have established a surface plasmon resonance (SPR) method for protein interaction analysis associated with coronavirus research and support the development and optimization of SPR methods. Coronavirus Surface Plasmon Resonance https://www.creative-biostructure.com/coronavirus/surface-plasmon-resonance-p34.htm
Detergent-free Protein Expression Service
from JoannaBowie1 on 01/31/2023 09:49 AMCreative Biostructure is specialized in providing cost-effective contract services to both academia and biotech/pharmaceutical industries in the field of structural biology and membrane protein technologies. We have developed all-in-one, gene-to-structure pipelines for the structure determination of macromolecules of your interest. With a team of experienced professionals, Creative Biostructure is able to solve the structure of many challenging proteins including GPCRs, ion channels, transporters, enzymes and viral targets. We also provide a comprehensive list of products and other related services to facilitate your research in structural biology. Detergent-free Protein Expression Service https://www.creative-biostructure.com/protein-detergent-free-expression-service-130.htm
Pharmacosomes
from JoannaBowie1 on 01/31/2023 09:49 AMCreative Biostructure is specialized in providing cost-effective contract services to both academia and biotech/pharmaceutical industries in the field of structural biology and membrane protein technologies. We have developed all-in-one, gene-to-structure pipelines for the structure determination of macromolecules of your interest. With a team of experienced professionals, Creative Biostructure is able to solve the structure of many challenging proteins including GPCRs, ion channels, transporters, enzymes and viral targets. We also provide a comprehensive list of products and other related services to facilitate your research in structural biology. Pharmacosomes https://www.creative-biostructure.com/Pharmacosomes-Production-615.htm